Medications
While medications to treat
bipolar disorder have been well studied for use in
adults, there are few long-term studies that confirm the effectiveness and
safety of mood stabilizers in children and adolescents with bipolar disorder.
Be sure to use all medications exactly as your child's doctor has prescribed
them. If your child develops intolerable side effects from any medication,
call your health professional immediately.
Medication Choices
Medications most often used to treat bipolar disorder in
children and adolescents include:
- Mood stabilizers, such as lithium (for
example, Eskalith, Lithane, or Lithobid), divalproex (Depakote), carbamazepine
(for example, Tegretol), lamotrigine (Lamictal),
oxcarbazepine (Trileptal), or
valproate (Depacon).
- Antipsychotics, such
as olanzapine (Zyprexa), risperidone (Risperdal), or aripiprazole (Abilify).
Antipsychotics may be combined with mood stabilizers for more effective control
of manic episodes.
- Antidepressants such as
selective serotonin reuptake inhibitors (SSRIs), like
fluoxetine (Prozac, for example), to control episodes of depression. (While
antidepressants can be helpful for some children with bipolar disorder, they
can also trigger
mania. Doctors usually prescribe antidepressants along
with mood stabilizers to help prevent a manic episode, and they need to
carefully monitor the child for mood changes.)
Before prescribing medicine to treat bipolar disorder,
your doctor will check your child for possible suicidal behavior by asking a
few questions. See a list of
questions your doctor may ask your child.
What To Think About
Deciding which medications to use
to treat bipolar disorder in children and adolescents can be a complicated
issue. Be sure to discuss all the options and side effects with your child's
doctor. Your child may have to try several medications or combinations of
medications before finding what works best. Some medications that seem to work
at first may not work in the long term. Carefully monitoring the effects of
medications is an ongoing process that is essential in identifying what is
working and what may need to be changed.
If the doctor prescribes
the mood stabilizer lithium carbonate, your child will need regular blood tests
to monitor the amount of lithium in the blood.
Too
much lithium may lead to serious side effects. Your child will also need
regular blood tests to monitor the amount of carbamazepine and divalproex in
the blood when using these medications.
When you and your child's
doctor are deciding which types of medications to use in the treatment of
bipolar disorder, consider:
- The side effects of each medication and how
well your child can tolerate them.
- How often your child will need
to take the medications.
- Whether your child is being treated for
other illnesses or disorders and how those medications will interact with
medications for bipolar disorder.
- Whether your child has used any
of the medications before and whether they worked.
FDA Advisory. The U.S. Food and
Drug Administration (FDA) has issued an
advisory on antidepressant medicines and the risk of
suicide. The FDA does not recommend that people stop using these medicines.
Instead, a person taking antidepressants should be watched for
warning signs of suicide. This is especially important
at the beginning of treatment or when the doses are changed.