unoprostone ophthalmic

Pronunciation:	uh no PROSS tone
Brand:	Rescula

What is the most important information I should know about unoprostone ophthalmic?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

Unoprostone ophthalmic may cause a change in the color of the eyes. The amount of brown pigment in the eyes may gradually increase during treatment with unoprostone ophthalmic. It is not known if these color changes are harmful or if they are reversible after therapy is discontinued.

What is unoprostone ophthalmic?

Unoprostone ophthalmic reduces pressure inside the eye by increasing the amount of fluid that drains from the eye.

Unoprostone ophthalmic is used to treat glaucoma or increased pressure in the eye(s).

Unoprostone ophthalmic may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using unoprostone ophthalmic?

Before using unoprostone ophthalmic, tell your doctor if you have

kidney disease;
liver disease; or
an eye infection, eye trauma, or require eye surgery.

You may not be able to use unoprostone ophthalmic, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Unoprostone ophthalmic is in the FDA pregnancy category C. This means that it is not known whether unoprostone ophthalmic will be harmful to an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is unknown whether unoprostone ophthalmic passes into breast milk. Do not use unoprostone ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use unoprostone ophthalmic?

Use unoprostone ophthalmic exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Unoprostone ophthalmic is usually used twice a day, one drop in the affected eye or eyes. Follow your doctor's instructions.

If you wear contact lenses, remove them before using unoprostone ophthalmic. Contact lenses may be reinserted 15 minutes after applying unoprostone eye drops.

Wash your hands before and after using the eyedrops.

To apply the eyedrops:

Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Steady the hand holding the bottle by placing your thumb against your brow or the bridge of your nose. Look up and away from the dropper. Gently press or lightly tap, the side of the bottle to allow only a single drop of medicine fall into the pocket formed by your lower eyelid. Do not allow the dropper to touch your eye. Close your eye for approximately 2 to 3 minutes. If you are using drops in both eyes, repeat this procedure in the other eye. If you are using more than one drop of unoprostone ophthalmic in the same eye, repeat the process in the same eye with about 5 minutes between drops.

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

Apply other eye medications at least 5 minutes before or after a dose of unoprostone ophthalmic, or as directed by your doctor.

Do not use any eyedrop that is discolored or has particles in it.

Store unoprostone ophthalmic at room temperature away from moisture and heat. Keep the bottle properly capped.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected or if the drops have been ingested.

Symptoms of an unoprostone ophthalmic overdose are not known.

What should I avoid while using unoprostone ophthalmic?

Do not touch the dropper to any surface, including the eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in the eye.

If you wear contact lenses, remove them before using unoprostone ophthalmic. Contact lenses may be reinserted 15 minutes after applying unoprostone eye drops.

Apply other eye medications at least 5 minutes before or after a dose of unoprostone ophthalmic, or as directed by your doctor.

What are the possible side effects of unoprostone ophthalmic?

If you experience any of the following serious side effects, stop using unoprostone ophthalmic and seek emergency medical attention or notify your doctor immediately:

an allergic reaction such as swelling of the lips, face, or tongue; difficulty breathing; closing of the throat; or hives;
physical injury to the eye(s); or
inflammation or redness of the eye or eyelids.

Other, less serious side effects may be more likely to occur. Continue to use unoprostone ophthalmic and talk to your doctor if you experience

burning or stinging of the eyes;
dryness of the eyes;
itching;
an increase or decrease in the length of the eyelashes;
abnormal vision;
a feeling of something in the eye; or
other problems with the eyelids or tears.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect unoprostone ophthalmic?

Before using unoprostone ophthalmic, tell your doctor if you are using another eye medication. Apply other eye medications at least 5 minutes before or after a dose of unoprostone ophthalmic, or as directed by your doctor.

Drugs other than those listed here may also interact with unoprostone ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Where can I get more information?

Your pharmacist has additional information about unoprostone ophthalmic written for health professionals that you may read.

What does my medication look like?

Unoprostone ophthalmic is available with a prescription under the brand name Rescula in a 0.15% solution. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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