ranitidine

Pronunciation:	ra NI ti deen
Brand:	Zantac, Zantac 150, Zantac 300, Zantac 300 GELdose, Zantac 75, Zantac EFFERdose, Zantac GELdose

What is the most important information I should know about ranitidine?

Before using this medication, tell your doctor if you are allergic to any drugs, or if you have kidney disease, liver disease, or porphyria.

Using ranitidine may increase your risk of developing pneumonia. Symptoms of pneumonia include chest pain, fever, feeling short of breath, and coughing up green or yellow mucous. Talk with your doctor about your specific risk of developing pneumonia.

Ranitidine granules and effervescent tablets must be dissolved in water before you take them.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Avoid drinking alcohol. It can increase the risk of damage to your stomach.

It may take up to 8 weeks of using this medicine before your ulcer heals. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 weeks of treatment.

What is ranitidine?

Ranitidine is in a group of drugs called histamine-2 blockers. Ranitidine works by reducing the amount of acid your stomach produces.

Ranitidine is used to treat and prevent ulcers in the stomach and intestines. It also treats conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome. Ranitidine also treats gastroesophageal reflux disease (GERD) and other conditions in which acid backs up from the stomach into the esophagus, causing heartburn.

Ranitidine may also be used for conditions other than those listed in this medication guide.

What should I discuss with my healthcare provider before using ranitidine?

Do not use this medication if you are allergic to ranitidine.

Before using ranitidine, tell your doctor if you are allergic to any drugs, or if you have:

kidney disease;
liver disease; or
porphyria.

If you have any of the conditions listed above, you may not be able to use ranitidine or you may need a dosage adjustment or special monitoring during treatment.

The ranitidine effervescent tablet may contain phenylalanine. Talk to your doctor before using this form of ranitidine if you have phenylketonuria (PKU).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Ranitidine passes into breast milk. Do not take ranitidine without telling your doctor if you are breast-feeding a baby.

How should I take ranitidine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Take each ranitidine tablet with a full glass of water.

Your doctor may recommend an antacid to help relieve pain. Carefully follow your doctor's directions about the type of antacid to use, and when to use it.

Do not crush, chew, or break the rantidine effervescent tablet, and do not allow it to dissolve on your tongue. The 25-milligram effervescent tablet must be dissolved in at least 1 teaspoon of water before swallowing. The150-milligram effervescent tablet should be dissolved in 6 to 8 ounces of water.

Allow the tablet to dissolve completely in the water, and then drink the entire mixture. If you are giving this medicine to a child, you may draw the liquid mixture into a medicine dropper and empty the dropper into the child's mouth.

Ranitidine granules should be mixed with 6 to 8 ounces of water before drinking.

Measure the liquid form of ranitidine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you are using ranitidine.

Store ranitidine at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Symptoms of a ranitidine overdose may include lack of coordination, feeling light-headed, or fainting.

What should I avoid while taking ranitidine?

Avoid drinking alcohol. It can increase the risk of damage to your stomach.

What are the possible side effects of ranitidine?

Stop using ranitidine and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

chest pain, fever, feeling short of breath, coughing up green or yellow mucous;
easy bruising or bleeding, unusual weakness;
fast or slow heart rate;
problems with your vision;
fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; or
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Other, less serious side effects may be more likely to occur, such as:

headache (may be severe);
drowsiness, dizziness;
sleep problems (insomnia);
decreased sex drive, impotence, or difficulty having an orgasm; or
swollen or tender breasts (in men);
nausea, vomiting, stomach pain; or
diarrhea or constipation.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect ranitidine?

Before taking ranitidine, tell your doctor if you are taking triazolam (Halcion). You may not be able to use ranitidine, or you may need dosage adjustments or special tests during treatment.

There may be other drugs that can affect ranitidine, or be affected by ranitidine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist has information about ranitidine written for health professionals that you may read.

What does my medication look like?

Ranitidine is available with a prescription under the brand name Zantac. It is also available over the counter under the brand name Zantac 75. Other brand and generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Zantac 150 mg Tablets--five-sided, peach-colored, film-coated tablets
Zantac 25 mg and 150 mg EFFERdose Tablets--round, white, flat-faced, beveled tablets
Zantac 150 mg EFFERdose Granules--white/pale-yellow granules
Zantac 300 mg Tablets--capsule-shaped, yellow, film-coated tablets
Zantac 300 mg Capsule--beige, soft-gelatin capsules
Zantac Syrup 15 mg/mL-clear, peppermint-flavored liquid

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2003 Cerner Multum, Inc. Version: 5.03. Revision date: 9/27/06.

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