Dupuytren's disease most commonly
affects people of northern European heritage. It is rare in people of African
or Asian descent. Heredity is thought to be a factor because Dupuytren's
disease tends to occur most often among close family members.
The
risk of Dupuytren's disease increases with age. It occurs most often in people
age 50 and older.1 Men are 7 to 15 times more likely
than women to have severe Dupuytren's disease that requires surgical treatment.
Older women often develop a milder form of the disease.2 Dupuytren's disease is very rare in children.
Up to 30% of men older than 65 with a Northern European genetic
background will have Dupuytren's disease.3 Many of
these will not need treatment.