Pregnant women and people who have
impaired immune systems or blood disorders are at risk
for developing complications from
fifth disease.
Treatment for pregnant women
In very rare cases, a fetus that becomes infected with parvovirus
B19 may develop severe anemia and swelling, a condition called
fetal hydrops. The mother and fetus should be closely
monitored with
fetal ultrasounds to detect this condition.
When fetal hydrops is detected, the fetus may be treated with blood
transfusions while in the uterus, although this is not usually
necessary.
Some babies born to mothers who were infected with fifth disease
during pregnancy may also be treated with blood transfusions.
Treatment for people who have blood or immune disorders
People who have blood disorders that cause anemia (such as
sickle cell disease or
thalassemia) may require
blood transfusions if a rapid worsening of existing
anemia (called transient aplastic anemia)
develops.
Intravenous immunoglobulin (IVIG) may be given to
people who have impaired immune systems to prevent a chronic parvovirus B19
infection and severe anemia.